CARD8 Rabbit pAb
application (WB, ELISA) & cross reactivity (Human)
$239.89 Commercial Only
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Product details
application (WB, ELISA) & cross reactivity (Human)
| Brand | ABclonal Technology |
|---|---|
| Manufacturer | ABclonal Technology |
| Product Size | 100ul |
| Size / Quantity | 1-EA |
Description
Size quantity: 1-EA Description: The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.
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